Molecular biology: table of contents
- Introduction
- Cells and genomes
- The universal features of cells:
Cells
- The diversity of genomes
- Genetic information in eukaryotes
- Cell chemistry and biosynthesis
- The chemical components of a cell
- Catalysis and the use of energy by cells |
Catalysis
- How cells obtain energy from food
- Proteins |
Proteins
- The shape and structure of proteins
- Protein function
- Basic genetic mechanisms
- DNA and chromosomes | DNA |
Chromosomes
- The structure and function of DNA
- Chromosomal DNA and its packaging in the chromatin
fiber
- The global structure of chromosomes
- DNA replication, repair, and recombination
- The maintenance of DNA sequences
- DNA replication mechanisms
- The initiation and completion of DNA replication in
chromosomes
- DNA repair
- General recombination
- Site-specific recombination
- From DNA to Protein
- From DNA to RNA
- From RNA to protein
- RNA world and the origins of life
- Control of gene expression
- An overview of gene control
- DNA-binding motifs in gene regulatory proteins
- How genetic switches work
- The molecular genetics mechanisms that create
specialized cell types
- Postranscriptional controls
- How genomes evolve
- Methods
- Manipulating proteins, DNA and RNA
- isolating cells and growing them in culture
- Fractionation of cells
- Isolating, cloning, and sequencing of DNA
- Analyzing protein structure and function
- Studying gene expression and function
- Visualizing cells
- Looking at the structure of cells in the microscope
- Visualizing molecules in living cells
- Internal organization of the cell
- Membrane structure
- Membrane transport of small molecules and the electrical
properties of membranes
- Principals of membrane transport
- Carrier proteins and active membrane transport
- Ion channels and the electrical properties of
membranes
- Intracellular compartments and protein sorting
- The compartmentalization of cells